Emergence of IntI1 associated blaVIM-2 gene cassette-mediated carbapenem resistance in opportunistic pathogen Pseudomonas stutzeri
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منابع مشابه
Emergence of IntI1 associated blaVIM-2 gene cassette-mediated carbapenem resistance in opportunistic pathogen Pseudomonas stutzeri
Dear Editor, Carbapenems are considered as the last resort of antibiotic for the treatment of infection but many Gram-negative organisms have developed resistance to this antibiotic through loss or alteration of outer membrane porin protein OprD, over-expression of efflux pump, hyperproduction of an AmpC-type-β-lactamase and/or carbapenemase.1 Carbapenemases are β-lactamases with catalytic effi...
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©2011 Elsevier Editora Ltda. All rights reserved. PCR analyses were performed with whole genomic DNA from all case isolates. Primers used for analysis of blaVIM /blaIMP genes were Vim F/R, Imp F/R respectively. PCR primers were designed and PCR conditions were performed as previously described.3 Association of integrons with MBL genes was confirmed by PCR using combination of blaand integron-sp...
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The emergence of carbapenem-resistant Pseudomonas aeruginosa in the lung of a patient with cystic fibrosis was evaluated. A single strain of P. aeruginosa persisted during a 3-year study despite antipseudomonal treatment. A stepwise decrease in carbapenem susceptibility leading to resistance was observed in the absence of carbapenem treatment. These data suggest that chronic exposure to unrelat...
متن کاملفراوانی سویه‌های تولیدکننده متالوبتالاکتامازدر پسودوموناس آئروژینوزای جداشده از بیماران سوختگی
Background: Pseudomonas aeruginosa is an important opportunistic pathogen causes clinical infections among burn patients. Metallo-β-lactamases (MBLs) are important mechanisms of Carbapenem (drug of choice) resistance among Pseudomonas aeruginosa isolates. The aims of this study were to determine the antibiotic susceptibility pattern and to detect the prevalence of MBLs among Pseudomonas aer...
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ژورنال
عنوان ژورنال: Emerging Microbes & Infections
سال: 2017
ISSN: 2222-1751
DOI: 10.1038/emi.2017.12